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BACKGROUND

Recently, in China, there is a concern of face masks sold on web containing detected level of Glucocorticoids.


WHAT IS GLUCOCORTICOIDS?

Glucocorticoids is a group of hormones, and is used in medication for dermatology for anti inflammatory action and suppression of immune response.
This group of hormones is not allowed in cosmetics products and is already restricted by China Food and Drug Administration under Hygienic Standard of Cosmetics 2007.
Some cosmetic products might have been illegally added Glucocorticoids to boost the whitening and smoothing effect on consumers in short time. However, long term and frequent usage of Glucocorticoids in cosmetics might have extreme reaction on skin, especially when high dosage of these hormones is applied. Red rash and dermatitis are common phenomena; skin will also become itchy and irritating to light.


ANALYSIS OF GLUCOCORTICOIDS CONTENT

Glucocorticoids in cosmetic products are restricted in various countries, including China, Europe and Canada. SGS can provide analysis of the following 41 Glucocorticoids which are prohibited in cosmetic products according to GB/T 24800.2-2009 in China. 

41 glucocorticoids (according to gb/t 24800.2-2009)

Substance Name CAS No.
Triamcinolone 124-94-7
Prednisolone 50-24-8
Hydrocortisone 50-23-7
Prednisone 53-03-2 
Cortisone 53-06-5
 Methylprednisolone  83-43-2
 Betamethasone  378-44-9 
 Dexamethasone  50-02-2
 Flumethasone  2135-17-3
 Beclomethasone  4419-39-0
 Triamcinolone acetonide  76-25-5
 Fludroxycortide  1524-88-5
 Triamcinolone Diacetate  67-78-7
 Prednisolone 21-acetat  52-21-1 
 Fluoromethalone  426-13-1 
 Hydrocortisone 21-acetate  50-03-3
 Deflazacort  14484-47-0
 Fludrocortisone 21-acetate  514-36-3
 Prednisone 21-Acetate  125-10-0 
 Cortisone 21-acetate  50-04-4
 Clobetasone 17-butyrate  25122-57-0 
 Methylprednisolone 21-acetate  53-36-1
 Betamethasone 21-acetate  987-24-6
 Budesonide  51372-29-3
 Hydrocortisone 17-butyrate  13609-67-1
 Dexamethasone 21-acetate  1177-87-3
 Fluorometholone 17-acetate  3801-06-7
 Hydrocortisone 17-valerate  57524-89-7
 Triamcinolone acetonide acetate  3870-07-3
 Fluocinonide  356-12-7
 Diflorasone diacetate  33564-31-7
 Betamethasone-17-valerate  2152-44-5
 Prednicarbate  73771-04-7
 Halcinonide  3093-35-4
 Alclomethasone dipropionate  66734-13-2
 Amcinonide  51022-69-6
 Clobetasol 17-propionate  25122-46-7
 Fluticasone propionate  80474-14-2
 Mometasone furoate  83919-23-7
 Betamethasone dipropionate  5593-20-4
 Beclometasone dipropionate  5534-09-8

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SGS HONG KONG LIMITED
Consumer and Retail
Cosmetics, Personal Care, and Household 
Customer Service Team

t +852 2609 9611
e HK.CPCH.CSTeam@sgs.com